Skip to contents

Mass-spectrometry based UPS proteomics data sets from Ramus C, Hovasse A, Marcellin M, Hesse AM, Mouton-Barbosa E, Bouyssie D, Vaca S, Carapito C, Chaoui K, Bruley C, Garin J, Cianferani S, Ferro M, Dorssaeler AV, Burlet-Schiltz O, Schaeffer C, Coute Y, Gonzalez de Peredo A. Spiked proteomic standard dataset for testing label-free quantitative software and statistical methods. Data Brief. 2015 Dec 17;6:286-94 and Giai Gianetto, Q., Combes, F., Ramus, C., Bruley, C., Coute, Y., Burger, T. (2016). Calibration plot for proteomics: A graphical tool to visually check the assumptions underlying FDR control in quantitative experiments. Proteomics, 16(1), 29-32.

Introduction

The DaparToolshedData package provides example quantitative data from proteomics experiments. The data are served through the ExperimentHub infrastructure, which allows download them only ones and cache them for further use. Currently available data are summarised in the table below and details in the next section.

## Warning: replacing previous import 'S4Arrays::makeNindexFromArrayViewport' by
## 'DelayedArray::makeNindexFromArrayViewport' when loading 'SummarizedExperiment'
##             Title
## 1   Exp1_R25_prot
## 2   Exp1_R25_pept
## 3    Exp1_R2_prot
## 4    Exp1_R2_pept
## 5    Exp2_R2_prot
## 6    Exp2_R2_pept
## 7   Exp2_R10_prot
## 8   Exp2_R10_pept
## 9  Exp2_R100_prot
## 10 Exp2_R100_pept
##                                                                                                 Description
## 1   Exp1_R25_prot 2 conditions, 3 replicates each and 2384 proteins, represented as a MultiAssayExperiment.
## 2  Exp1_R25_pept 2 conditions, 3 replicates each and 13919 peptides, represented as a MultiAssayExperiment.
## 3    Exp1_R2_prot 2 conditions, 3 replicates each and 2394 proteins, represented as a MultiAssayExperiment.
## 4   Exp2_R2_pept 2 conditions, 3 replicates each and 14048 peptides, represented as a MultiAssayExperiment.
## 5     Exp2_R2_prot 2 conditions, 3 replicates each and 948 proteins, represented as a MultiAssayExperiment.
## 6    Exp2_R2_pept 2 conditions, 3 replicates each and 5390 peptides, represented as a MultiAssayExperiment.
## 7    Exp2_R10_prot 2 conditions, 3 replicates each and 948 proteins, represented as a MultiAssayExperiment.
## 8  Exp2_R100_pept 2 conditions, 3 replicates each and 5684 peptides, represented as a MultiAssayExperiment.
## 9   Exp2_R100_prot 2 conditions, 3 replicates each and 923 proteins, represented as a MultiAssayExperiment.
## 10 Exp2_R100_pept 2 conditions, 3 replicates each and 5684 peptides, represented as a MultiAssayExperiment.
##    BiocVersion Genome SourceType                           SourceUrl
## 1         3.23     NA      RData https://zenodo.org/records/18592150
## 2         3.23     NA      RData https://zenodo.org/records/18592150
## 3         3.23     NA      RData https://zenodo.org/records/18592150
## 4         3.23     NA      RData https://zenodo.org/records/18592150
## 5         3.23     NA      RData https://zenodo.org/records/18592150
## 6         3.23     NA      RData https://zenodo.org/records/18592150
## 7         3.23     NA      RData https://zenodo.org/records/18592150
## 8         3.23     NA      RData https://zenodo.org/records/18592150
## 9         3.23     NA      RData https://zenodo.org/records/18592150
## 10        3.23     NA      RData https://zenodo.org/records/18592150
##    SourceVersion      Species TaxonomyId Coordinate_1_based DataProvider
## 1    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 2    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 3    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 4    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 5    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 6    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 7    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 8    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 9    Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
## 10   Feb 10 2026 Homo sapiens         NA               TRUE     EDyP-lab
##                                    Maintainer           RDataClass
## 1  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 2  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 3  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 4  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 5  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 6  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 7  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 8  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 9  Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
## 10 Samuel Wieczorek <samuel.wieczorek@cea.fr> MultiAssayExperiment
##    DispatchClass     Location_Prefix
## 1       FilePath https://zenodo.org/
## 2       FilePath https://zenodo.org/
## 3       FilePath https://zenodo.org/
## 4       FilePath https://zenodo.org/
## 5       FilePath https://zenodo.org/
## 6       FilePath https://zenodo.org/
## 7       FilePath https://zenodo.org/
## 8       FilePath https://zenodo.org/
## 9       FilePath https://zenodo.org/
## 10      FilePath https://zenodo.org/
##                                      RDataPath Tags Notes
## 1   records/18592150/files/Exp1_R25_prot.RData   NA    NA
## 2   records/18592150/files/Exp1_R25_pept.RData   NA    NA
## 3    records/18592150/files/Exp1_R2_prot.RData   NA    NA
## 4    records/18592150/files/Exp1_R2_pept.RData   NA    NA
## 5    records/18592150/files/Exp2_R2_prot.RData   NA    NA
## 6    records/18592150/files/Exp2_R2_pept.RData   NA    NA
## 7   records/18592150/files/Exp2_R10_prot.RData   NA    NA
## 8   records/18592150/files/Exp2_R10_pept.RData   NA    NA
## 9  records/18592150/files/Exp2_R100_prot.RData   NA    NA
## 10 records/18592150/files/Exp2_R100_pept.RData   NA    NA

Installation

To install the package:

if (!require("BiocManager"))
    install.packages("BiocManager")

BiocManager::install("DaparToolshedData")

Available data

Load datasets with (example for the Exp1_R25_prot dataset)

GetData('Exp1_R25_prot')

sessionInfo()

## R version 4.6.0 (2026-04-24)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.4 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.26.so;  LAPACK version 3.12.0
## 
## locale:
##  [1] LC_CTYPE=C.UTF-8       LC_NUMERIC=C           LC_TIME=C.UTF-8       
##  [4] LC_COLLATE=C.UTF-8     LC_MONETARY=C.UTF-8    LC_MESSAGES=C.UTF-8   
##  [7] LC_PAPER=C.UTF-8       LC_NAME=C              LC_ADDRESS=C          
## [10] LC_TELEPHONE=C         LC_MEASUREMENT=C.UTF-8 LC_IDENTIFICATION=C   
## 
## time zone: UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats     graphics  grDevices utils     datasets  methods   base     
## 
## other attached packages:
## [1] DaparToolshedData_0.99.17 BiocStyle_2.40.0         
## 
## loaded via a namespace (and not attached):
##  [1] tidyselect_1.2.1            dplyr_1.2.1                
##  [3] blob_1.3.0                  Biostrings_2.80.1          
##  [5] filelock_1.0.3              fastmap_1.2.0              
##  [7] lazyeval_0.2.3              BiocFileCache_3.2.0        
##  [9] digest_0.6.39               lifecycle_1.0.5            
## [11] cluster_2.1.8.2             ProtGenerics_1.44.0        
## [13] KEGGREST_1.52.0             RSQLite_3.53.1             
## [15] magrittr_2.0.5              compiler_4.6.0             
## [17] rlang_1.2.0                 sass_0.4.10                
## [19] tools_4.6.0                 igraph_2.3.2               
## [21] yaml_2.3.12                 knitr_1.51                 
## [23] S4Arrays_1.12.0             htmlwidgets_1.6.4          
## [25] bit_4.6.0                   curl_7.1.0                 
## [27] DelayedArray_0.38.2         plyr_1.8.9                 
## [29] abind_1.4-8                 purrr_1.2.2                
## [31] BiocGenerics_0.58.1         desc_1.4.3                 
## [33] grid_4.6.0                  stats4_4.6.0               
## [35] ExperimentHub_3.2.0         MASS_7.3-65                
## [37] MultiAssayExperiment_1.38.0 SummarizedExperiment_1.42.0
## [39] cli_3.6.6                   crayon_1.5.3               
## [41] rmarkdown_2.31              ragg_1.5.2                 
## [43] generics_0.1.4              otel_0.2.0                 
## [45] httr_1.4.8                  reshape2_1.4.5             
## [47] DBI_1.3.0                   cachem_1.1.0               
## [49] stringr_1.6.0               AnnotationDbi_1.74.0       
## [51] AnnotationFilter_1.36.0     BiocManager_1.30.27        
## [53] XVector_0.52.0              matrixStats_1.5.0          
## [55] vctrs_0.7.3                 Matrix_1.7-5               
## [57] jsonlite_2.0.0              bookdown_0.46              
## [59] IRanges_2.46.0              S4Vectors_0.50.1           
## [61] bit64_4.8.2                 clue_0.3-68                
## [63] systemfonts_1.3.2           tidyr_1.3.2                
## [65] jquerylib_0.1.4             glue_1.8.1                 
## [67] pkgdown_2.2.0               QFeatures_1.22.0           
## [69] stringi_1.8.7               BiocVersion_3.23.1         
## [71] GenomicRanges_1.64.0        tibble_3.3.1               
## [73] pillar_1.11.1               rappdirs_0.3.4             
## [75] htmltools_0.5.9             Seqinfo_1.2.0              
## [77] R6_2.6.1                    dbplyr_2.5.2               
## [79] httr2_1.2.2                 textshaping_1.0.5          
## [81] evaluate_1.0.5              lattice_0.22-9             
## [83] Biobase_2.72.0              AnnotationHub_4.2.0        
## [85] png_0.1-9                   memoise_2.0.1              
## [87] bslib_0.11.0                Rcpp_1.1.1-1.1             
## [89] SparseArray_1.12.2          xfun_0.58                  
## [91] MsCoreUtils_1.24.0          fs_2.1.0                   
## [93] MatrixGenerics_1.24.0       pkgconfig_2.0.3